In the 13th century, the Egyptian physician al-Nafis (1213-1288) became the first person to and pulmonary circulation. He published understanding of circulation in Commentary on in Avicenna's Cannon, but his knowledge to reach Europe.
Three centuries later, in 1553, Spanish doctor Michael (circa 1509 or 1511-1553) proposed a theory ary circulation. It was never shared though the Catholic Church burned him at the stake heretical views.
Finally, six years later, Italian anatomist Matteo Colombo (1516-1559) would rediscover the which he published in 1559 in his anatomy text, Anatomical Matters. Colombo understood the of the heart: how it contracts and pushes blood into the arteries. He is recognized for his understanding of how blood circulates from the heart's right ventricle to the lungs then returns,to the heart's left atrium—a major step toward understanding general circulation as we know it today.